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Cheapest
Best Offer!
Car
6 h 32 min
669 km.
from $36
Composite Route Car Only
Schedule
Rome, Italy → Melendugno, Italy
All
31 juil. 2026
July 2026
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Cheapest and Fastest Ways to Travel from Rome to Melendugno
Composite routes from Rome to Melendugno
Cheapest
6 h 32 min
Car
Other
5 h 43 min
Plane, Train, Bus
Route Navigator Rome - Melendugno
Get all the information you need right here
Continue onto Via dell'Umiltà
Via dell'Umiltà, 55 м
55 м
Turn left onto Via dell'Archetto
Via dell'Archetto, 115 м
115 м
Turn right onto Via del Vaccaro
Via del Vaccaro, 38 м
38 м
Turn left onto Piazza dei Santi Apostoli
Piazza dei Santi Apostoli, 181 м
181 м
Turn sharp left onto Via Quattro Novembre
Via Quattro Novembre, 386 м
386 м
Turn right onto Largo Angelicum
Largo Angelicum, 20 м
20 м
Turn left onto Via Panisperna
Via Panisperna, 135 м
135 м
Keep right onto Via di Sant'Agata de' Goti
Via di Sant'Agata de' Goti, 178 м
178 м
Turn left onto Via Baccina
Via Baccina, 95 м
95 м
Turn right onto Via dei Serpenti
Via dei Serpenti, 95 м
95 м
Turn left onto Via Cavour
Via Cavour, 196 м
196 м
Keep right onto Largo Visconti Venosta
Largo Visconti Venosta, 1 km 584 м
1 km 584 м
Continue onto Via dello Statuto
Via dello Statuto, 469 м
469 м
Turn left onto Piazza Vittorio Emanuele Secondo
Piazza Vittorio Emanuele Secondo, 135 м
135 м
Turn right onto Via Principe Eugenio
Via Principe Eugenio, 314 м
314 м
Continue onto Via di Porta Maggiore
Via di Porta Maggiore, 378 м
378 м
Keep left onto Piazza di Porta Maggiore
Piazza di Porta Maggiore, 141 м
141 м
Keep left onto Piazza di Porta Maggiore
Piazza di Porta Maggiore, 97 м
97 м
Keep right onto Piazzale Labicano
Piazzale Labicano, 465 м
465 м
Continue onto Via Prenestina
Via Prenestina, 1 km 622 м
1 km 622 м
Turn right
1 km 537 м
1 km 537 м
Continue onto Via Casilina
Via Casilina, 5 km 649 м
5 km 649 м
Continue onto Via Casilina
Via Casilina, 2 km 952 м
2 km 952 м
Keep right
1 km 799 м
1 km 799 м
Keep right
253 м
253 м
Keep right
458 м
458 м
Continue onto Diramazione Roma Sud
Diramazione Roma Sud, 143 km 137 м
143 km 137 м
Keep right and drive toward Caianello
Caianello, 1 km 854 м
1 km 854 м
Keep right onto Strada Statale 372 Telesina
Strada Statale 372 Telesina, 6 km 381 м
6 km 381 м
Keep right and drive toward Pietravairano
Pietravairano, 150 м
150 м
Keep left and drive toward Pietravairano
Pietravairano, 31 м
31 м
Turn right
215 м
215 м
Turn slight right onto Strada Statale 372 Telesina
Strada Statale 372 Telesina, 4 km 140 м
4 km 140 м
Keep right and drive toward Baia e Latina, Piedimonte
Baia e Latina, Piedimonte, 251 м
251 м
Keep left and drive toward Pietravairano, Alife
Pietravairano, Alife, 31 м
31 м
Turn right
239 м
239 м
Continue onto Strada Statale 372 Telesina
Strada Statale 372 Telesina, 59 km 850 м
59 km 850 м
Keep left onto Raccordo autostradale 9 di Benevento
Raccordo autostradale 9 di Benevento, 13 km 333 м
13 km 333 м
Keep right
103 km 172 м
103 km 172 м
Keep right onto Autostrada dei Due Mari and drive toward Bari
Autostrada dei Due Mari, Bari, 69 km 331 м
69 km 331 м
Keep right onto Raccordo A14-Tangenziale di Bari
Raccordo A14-Tangenziale di Bari, 191 м
191 м
Keep left onto Raccordo A14-Tangenziale di Bari
Raccordo A14-Tangenziale di Bari, 4 km 408 м
4 km 408 м
Keep right and drive toward Bari Centro, Taranto, Brindisi, Lecce, Sacrario Militare Caduti Oltremare
Bari Centro, Taranto, Brindisi, Lecce, Sacrario Militare Caduti Oltremare, 153 km 614 м
153 km 614 м
At roundabout, take exit 2 onto Viale Porta d'Europa
Viale Porta d'Europa, 308 м
308 м
At roundabout, take exit 3 onto Viale Michele De Pietro
Viale Michele De Pietro, 1 km 702 м
1 km 702 м
Keep left onto Viale Michele De Pietro
Viale Michele De Pietro, 8 м
8 м
At roundabout, take exit 2 onto Via Giuseppe Garibaldi
Via Giuseppe Garibaldi, 1 km 669 м
1 km 669 м
At roundabout, take exit 2 onto Via Giovanni Antonio Orsini Del Balzo
Via Giovanni Antonio Orsini Del Balzo, 466 м
466 м
At roundabout, take exit 2 onto Viale Torre del Parco
Viale Torre del Parco, 409 м
409 м
At roundabout, take exit 3 onto Viale Gioacchino Rossini
Viale Gioacchino Rossini, 307 м
307 м
Turn right onto Via Merine
Via Merine, 1 km 358 м
1 km 358 м
At roundabout, take exit 2 onto Via Vernole
Via Vernole, 1 km 620 м
1 km 620 м
At roundabout, take exit 2 onto Strada Provinciale Lecce - Vernole
Strada Provinciale Lecce - Vernole, 1 km 429 м
1 km 429 м
At roundabout, take exit 3 onto Strada Provinciale Lecce - Vernole
Strada Provinciale Lecce - Vernole, 1 km 754 м
1 km 754 м
At roundabout, take exit 2 onto Strada Provinciale Lecce - Vernole
Strada Provinciale Lecce - Vernole, 1 km 601 м
1 km 601 м
At roundabout, take exit 2 onto Strada Provinciale Lecce - Vernole
Strada Provinciale Lecce - Vernole, 2 km 270 м
2 km 270 м
At roundabout, take exit 2 onto Strada Provinciale Lecce - Vernole
Strada Provinciale Lecce - Vernole, 2 km 899 м
2 km 899 м
At roundabout, take exit 2 onto Strada Provinciale Lecce - Vernole
Strada Provinciale Lecce - Vernole, 3 km 670 м
3 km 670 м
Keep left onto Strada Provinciale Vernole - Melendugno
Strada Provinciale Vernole - Melendugno, 1 km 293 м
1 km 293 м
At roundabout, take exit 2 onto Strada Provinciale Vernole - Melendugno
Strada Provinciale Vernole - Melendugno, 3 km 824 м
3 km 824 м
Keep right
1 km 879 м
1 km 879 м
Turn left onto Piazza Sandro Pertini
Piazza Sandro Pertini, 45 м
45 м
Turn left onto Piazza Sandro Pertini
Piazza Sandro Pertini, 42 м
42 м
Turn left onto Piazza Sandro Pertini
Piazza Sandro Pertini, 21 м
21 м
Arrive at destination
Transport providers
Airlines
Ryanair
Website:
ryanair.com/
Plane from Leonardo Da Vinci–Fiumicino Airport to Papola
Ave. Duration:
1h 15m
Frequency:
Every day
Estimated price:
$15.24–$241.37
Alitalia
Website:
alitalia.com/
Plane from Leonardo Da Vinci–Fiumicino Airport to Papola
Ave. Duration:
1h 10m
Frequency:
Every day
Estimated price:
$58.44–$368.41
Bus operators
FlixBus
Phone:
+49 30 300 137 300
Email:
service@flixbus.com
Website:
flixbus.com
Bus from Roma, Autostazione Tiburtina to Lecce
Ave. Duration:
8h 20m
Frequency:
Every 4 hours
Estimated price:
$59.71–$88.93
Itabus
Phone:
+39 06 88 93 82 32
Website:
itabus.it/en/home
Bus from Roma, Autostazione Tiburtina to Lecce
Ave. Duration:
8h 25m
Frequency:
3 times a day
Estimated price:
$26.68–$38.11
Bus from Fiumicino Aeroporto T3 to Lecce
Ave. Duration:
10h 25m
Frequency:
6 times a week
Estimated price:
$29.22–$40.65
Marino Autolinee
Phone:
+39 080 3112335
Email:
info@marinobus.it
Website:
marinobus.it/
Bus from Roma, Autostazione Tiburtina to Lecce
Ave. Duration:
8h 10m
Frequency:
Twice daily
Estimated price:
$57.17–$76.22
TTI Leonettibus SRL
Phone:
+39081969167
Email:
servizioclienti@leonettiroma.it
Website:
leonettiroma.it/
Bus from Roma, Autostazione Tiburtina to Lecce
Ave. Duration:
9h 15m
Frequency:
Once a week
Estimated price:
$40.65–$59.71
Ferrovie del Sud Est e Servizi Automobilistici
Phone:
+39 800 079 090
Website:
fseonline.it/s/?language=it
Bus from Lecce - Via Don Bosco to Melendugno
Ave. Duration:
35 min
Frequency:
Once daily
Estimated price:
$2.16–$3.18
Train operators
Trenitalia
Phone:
+39 06 68475475
Website:
trenitalia.com/
Train from Brindisi to Lecce
Ave. Duration:
30 min
Frequency:
Hourly
Estimated price:
$4.83–$8.89
Trenitalia Frecce
Phone:
+39 06 68475475
Website:
trenitalia.com/en/frecce.html
Train from Roma Termini to Lecce
Ave. Duration:
5h 44m
Frequency:
5 times a day
Estimated price:
$54.63–$165.15
Train from Brindisi to Lecce
Ave. Duration:
26 min
Frequency:
Every 3 hours
Estimated price:
$8.89–$45.73
Trenitalia Intercity
Phone:
+39 06 68475475
Website:
trenitalia.com/
Train from Brindisi to Lecce
Ave. Duration:
28 min
Frequency:
Every 4 hours
Estimated price:
$5.84–$8.26
Questions and Answers
What is the cheapest way to get from Rome to Melendugno?
The cheapest way to get from Rome to Melendugno is to night bus which costs $29.35 - $46.74 and takes 14h 15m.
What is the fastest way to get from Rome to Melendugno?
The fastest way to get from Rome to Melendugno is to fly and train and bus which takes 5h 43m and costs $26.09 - $271.74 .
Is there a direct bus between Rome and Melendugno?
No, there is no direct bus from Rome to Melendugno. However, there are services departing from Roma, Autostazione Tiburtina and arriving at Melendugno via City Terminal and Lecce - Via Don Bosco. The journey, including transfers, takes approximately 10h 15m.
How far is it from Rome to Melendugno?
The distance between Rome and Melendugno is 651 km. The road distance is 667.9 km.
How do I travel from Rome to Melendugno without a car?
The best way to get from Rome to Melendugno without a car is to train which takes 7h 24m and costs $48.91 - $141.30 .
How long does it take to get from Rome to Melendugno?
It takes approximately 7h 24m to get from Rome to Melendugno, including transfers.
Where do I catch the Rome to Melendugno bus from?
Rome to Melendugno bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Train or bus from Rome to Melendugno?
The best way to get from Rome to Melendugno is to train which takes 7h 24m and costs $48.91 - $141.30 . Alternatively, you can bus, which costs $26.09 - $76.09 and takes 10h 15m.
Where does the Rome to Melendugno bus arrive?
Rome to Melendugno bus services, operated by FlixBus, arrive at Lecce station.
Can I drive from Rome to Melendugno?
Yes, the driving distance between Rome to Melendugno is 668 km. It takes approximately 6h 29m to drive from Rome to Melendugno.
Where can I stay near Melendugno?
There are 3181+ hotels available in Melendugno. Prices start at $57.26 per night.
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