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How to Travel from

Karpathos to Mytilene

by Plane, Route or Car

Karpathos
→
+0 →
Mytilene
Transport search to Mytilene
Simply select points
A and B, and we will create
a convenient route for you 👍
Greece Karpathos Mytilene
Karpathos
→
+0 →
Mytilene
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A and B, and we will create
a convenient route for you 👍
To build a composite route, click the "Add point" button.
You can also move and delete intermediate points.
Cheapest
Best Offer!
Car
21 h 50 min
672 km.
from $36
Composite Route Car Only
Schedule

Karpathos, Greece → Mytilene, Greece

All
29 juil. 2026
July 2026
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Cheapest and Fastest Ways to Travel from Karpathos to Mytilene

Composite routes from Karpathos to Mytilene

Cheapest
21 h 50 min
Car
672 km.
from $36
Other
17 h 42 min
Ferry, Bus
400 km.
Select a ticket
9 h 8 min
Ferry, Plane
403 km.
from $212.66
12 h 23 min
Bus, Plane
403 km.
from $177.93
18 h 4 min
Ferry, bus via İzmir
404 km.
from $5.43
19 h 15 min
Ferry
402 km.
from $245.84

Transport providers

Airlines

Aegean Airlines

Website:
en.aegeanair.com/
Plane from Karpathos Island National Airport to Mytilene
Ave. Duration:
5h 40m
Frequency:
Thursday
Estimated price:
$82.80–$242.02
Plane from Diagoras International Airport to Mytilene
Ave. Duration:
3h 53m
Frequency:
Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
Estimated price:
$63.69–$242.02
Plane from Karpathos Island National Airport to Chios
Ave. Duration:
7h 40m
Frequency:
Tuesday, Thursday, and Saturday
Estimated price:
$70.06–$203.80

Sky Express

Website:
skyexpress.gr/
Plane from Karpathos Island National Airport to Mytilene
Ave. Duration:
8h 20m
Frequency:
Monday, Wednesday, Friday, and Sunday
Estimated price:
$63.69–$267.49
Plane from Diagoras International Airport to Mytilene
Ave. Duration:
5h 2m
Frequency:
Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
Estimated price:
$63.69–$267.49
Plane from Karpathos Island National Airport to Chios
Ave. Duration:
8h
Frequency:
Monday, Wednesday, Friday, and Sunday
Estimated price:
$56.05–$229.28

Bus operators

Pamukkale

Phone:
0 850 333 35 35
Email:
info@pamukkale.com.tr
Website:
pamukkale.com.tr
Bus from Marmaris to İzmir
Ave. Duration:
4h 15m
Frequency:
Every 3 hours
Estimated price:
$10.83–$15.29

Kale Seyahat

Phone:
0850 811 5959
Email:
website@kaleseyahat.com.tr
Website:
kaleseyahat.com.tr/
Bus from İzmir to Dikili
Ave. Duration:
1h 40m
Frequency:
3 times a day

Truva

Phone:
0 286 212 22 22
Email:
info@truvaturizm.com
Website:
truvaturizm.com/
Bus from Marmaris to Aliağa
Ave. Duration:
5h 8m
Frequency:
Once a week

Metro Turizm

Phone:
0850 222 34 55
Email:
iletisim@metroturizm.com.tr
Website:
metroturizm.com.tr/en
Bus from Aliaga to Ayvalik
Ave. Duration:
1h 58m
Frequency:
3 times a day
Estimated price:
$9.55–$14.01
Bus from Marmaris to İzmir
Ave. Duration:
3h 30m
Frequency:
Twice daily
Estimated price:
$11.46–$16.56

Other operators

Sea Dreams

Phone:
+30 22410 74 235
Email:
info@seadreams.gr
Website:
seadreams.gr/
Other from Port of Rhodes to Port
Ave. Duration:
1h
Frequency:
4 times a week
Estimated price:
$58.14

Yeşil Marmaris Lines

Phone:
+90 (252) 412 22 90 – 91
Email:
reservation@yesilmarmaris.com
Website:
yesilmarmarislines.com/
Other from Port of Rhodes to Port
Ave. Duration:
1h
Frequency:
3 times a week
Estimated price:
$68.36

Makri Travel

Phone:
+30 694 415 6070
Email:
info@makritravel.com
Website:
makritravel.com/tr/
Other from Port of Ayvalik to Mytilene
Ave. Duration:
1h 15m
Frequency:
Once daily
Estimated price:
$37.28

Blue Star Ferries

Phone:
+302108919800
Email:
bluestarferries@bluestarferries.com
Website:
bluestarferries.com/en-gb/
Other from Karpathos to Halki
Ave. Duration:
2h 25m
Frequency:
Twice a week
Estimated price:
$30.57–$95.53
Other from Port of Kos to Vathy
Ave. Duration:
4h 25m
Frequency:
3 times a week
Estimated price:
$38.21–$108.27
Other from Vathy Samou to Mytilene
Ave. Duration:
5h 10m
Frequency:
Twice a week
Estimated price:
$39.49–$108.27
Other from Karpathos to Port
Ave. Duration:
3h 50m
Frequency:
3 times a week
Estimated price:
$35.67–$101.90
Other from Chios to Mytilene
Ave. Duration:
3h
Frequency:
Once daily
Estimated price:
$30.57–$95.53
Other from Port of Rhodes to Vathy
Ave. Duration:
8h 15m
Frequency:
3 times a week
Estimated price:
$47.13–$121.01
Other from Fourni to Mytilene
Ave. Duration:
7h 50m
Frequency:
Twice a week
Estimated price:
$47.13–$121.01

Hellenic Seaways

Phone:
+30 210 89 19 800
Email:
hellenicseaways@hellenicseaways.gr
Website:
hellenicseaways.gr/
Other from Chios to Mytilene
Ave. Duration:
3h
Frequency:
Once a week
Estimated price:
$31.84–$108.27

Dodekanisos Seaways

Phone:
+30 22410 70590
Email:
info@12ne.gr
Website:
12ne.gr/en
Other from Chalki to Port
Ave. Duration:
2h 25m
Frequency:
Once a week
Estimated price:
$35.67–$47.13
Other from Port of Kalymnos to Fourni
Ave. Duration:
2h 55m
Frequency:
3 times a week
Estimated price:
$40.76–$54.77

Questions and Answers

What is the cheapest way to get from Karpathos to Mytilene?

The cheapest way to get from Karpathos to Mytilene is to fly which costs $65.22 - $217.39 and takes 7h 18m.

What is the fastest way to get from Karpathos to Mytilene?

The fastest way to get from Karpathos to Mytilene is to fly which takes 7h 18m and costs $65.22 - $217.39 .

Is there a direct ferry between Karpathos and Mytilene?

No, there is no direct ferry from Karpathos to Mytilene. However, there are services departing from Karpathos and arriving at Mytilene via Chalki, Port of Kos and Vathy Samou. The journey, including transfers, takes approximately 17h 25m.

How far is it from Karpathos to Mytilene?

The distance between Karpathos and Mytilene is 431 km.

How do I get a ferry ticket from Karpathos to Mytilene?

Book your Karpathos to Mytilene ferry tickets online with Omio.

How do I travel from Karpathos to Mytilene without a car?

The best way to get from Karpathos to Mytilene without a car is to ferry and car ferry which takes 17h 25m and costs $119.57 - $315.22 .

How long does it take to get from Karpathos to Mytilene?

It takes approximately 7h 18m to get from Karpathos to Mytilene, including transfers.

What is the time difference between Karpathos and Mytilene?

It is currently 10:24 at both, Karpathos and Mytilene.

Where can I stay near Mytilene?

There are 312+ hotels available in Mytilene. Prices start at $37.11 per night.
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