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Cheapest
Best Offer!
Car
7 h 51 min
704 km.
from $38
Composite Route Car Only
Schedule
La Serena, Chile → Mendoza, Argentina
All
10 août 2026
August 2026
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Cheapest and Fastest Ways to Travel from La Serena to Mendoza
Composite routes from La Serena to Mendoza
Cheapest
7 h 51 min
Car
Other
12 h 19 min
15 h 6 min
15 h 44 min
Route Navigator La Serena - Mendoza
Get all the information you need right here
Continue onto Eduardo de la Barra
Eduardo de la Barra, 1 km 503 м
1 km 503 м
Turn left onto Pedro Pablo Muñoz
Pedro Pablo Muñoz, 70 м
70 м
Keep right
59 м
59 м
Turn right onto Avenida Francisco de Aguirre
Avenida Francisco de Aguirre, 264 м
264 м
Turn left onto Ruta 5 Norte and drive toward La Serena
Ruta 5 Norte, La Serena, 342 km 495 м
342 km 495 м
Keep left onto Ruta 5 Norte
Ruta 5 Norte, 40 km 618 м
40 km 618 м
Keep right and take 60 toward Los Andes, Portillo
Los Andes, Portillo, 60, 115 м
115 м
Turn slight right onto Autopista Los Andes
Autopista Los Andes, 51 km 640 м
51 km 640 м
Keep right and take E-61 toward Los Andes
Los Andes, E-61, 218 м
218 м
Turn sharp left onto Camino Internacional
Camino Internacional, 204 km 290 м
204 km 290 м
Keep left onto Empalme con Ruta Provincial 89
Empalme con Ruta Provincial 89, 1 km 605 м
1 km 605 м
Keep right onto RP82
164 м
164 м
At roundabout, take exit 1 onto Camino del Perilago
Camino del Perilago, 1 km 279 м
1 km 279 м
At roundabout, take exit 2 onto Camino del Perilago
Camino del Perilago, 3 km 62 м
3 km 62 м
At roundabout, take exit 1 onto RP82
24 km 856 м
24 km 856 м
Keep left onto Panamericana
Panamericana, 5 km 680 м
5 km 680 м
At roundabout, take exit 2 onto Panamericana
Panamericana, 2 km 102 м
2 km 102 м
Keep left onto Panamericana
Panamericana, 5 km 875 м
5 km 875 м
Keep right onto RP82
208 м
208 м
At roundabout, take exit 2 onto Panamericana
Panamericana, 411 м
411 м
At roundabout, take exit 2 onto Panamericana
Panamericana, 1 km 300 м
1 km 300 м
At roundabout, take exit 2 onto Panamericana
Panamericana, 2 km 557 м
2 km 557 м
At roundabout, take exit 2 onto Avenida General San Martín Sur
Avenida General San Martín Sur, 1 km 706 м
1 km 706 м
Turn right onto Mariano Sánchez de Loria Oeste
Mariano Sánchez de Loria Oeste, 282 м
282 м
Turn left onto Perito Moreno
Perito Moreno, 2 km 889 м
2 km 889 м
Turn right onto Ignacio Álvarez Thomas
Ignacio Álvarez Thomas, 1 km 566 м
1 km 566 м
Turn left onto Miguel de Cervantes
Miguel de Cervantes, 200 м
200 м
At roundabout, take exit 3 onto Remedios de Escalada de San Martín
Remedios de Escalada de San Martín, 1 km 652 м
1 km 652 м
Turn left
3 km 783 м
3 km 783 м
Keep left onto Gobernador Ricardo Videla
Gobernador Ricardo Videla, 2 km 725 м
2 km 725 м
Turn right onto Uruguay
Uruguay, 386 м
386 м
Turn left onto Francisco de la Reta
Francisco de la Reta, 59 м
59 м
Turn right onto Justo Santa María de Oro
Justo Santa María de Oro, 261 м
261 м
Turn left onto Juan Galo de Lavalle
Juan Galo de Lavalle, 209 м
209 м
Turn right onto Correa Saa
Correa Saa, 410 м
410 м
Arrive at destination
Transport providers
Airlines
JetSMART
Website:
jetsmart.com/
Plane from La Florida Airport to Governor
Ave. Duration:
4h 26m
Frequency:
Friday
Estimated price:
$47.83–$119.57
Sky Airline
Website:
skyairline.com/
Plane from La Florida Airport to Governor
Ave. Duration:
4h 6m
Frequency:
Tuesday
Estimated price:
$108.70–$456.52
LATAM Chile
Website:
latam.com/
Plane from La Florida Airport to Governor
Ave. Duration:
3h 35m
Frequency:
Wednesday and Sunday
Estimated price:
$206.52–$445.65
Bus operators
Andesmar
Phone:
0810 122 1122
Email:
gestionesatc@andesmar.com.ar
Website:
andesmar.com/es
Bus from Terminal Sur de Santiago to Terminal
Ave. Duration:
8h
Frequency:
4 times a day
Estimated price:
$18.48–$34.78
Cata Internacional
Phone:
0800 122 2282
Email:
atencionalcliente@catainternacional.com
Website:
catainternacional.com/
Bus from Terminal Sur de Santiago to Terminal
Ave. Duration:
8h
Frequency:
Every 4 hours
Estimated price:
$18.48–$40.49
Pullman Bus
Phone:
+56 600 600 0018
Email:
clientes@pullmanbus.cl
Website:
pullmanbus.cl
Bus from Terminal de Buses La Serena to La
Ave. Duration:
4h 25m
Frequency:
Once daily
Estimated price:
$22.83–$31.52
Turbus
Phone:
+56 22 822 7500
Email:
atencion_clientes@turbus.cl
Website:
turbus.cl/
Bus from Terminal de Buses La Serena to Terminal
Ave. Duration:
6h 25m
Frequency:
Hourly
Estimated price:
$14.13–$38.04
Bus from Terminal Sur de Santiago to Terminal
Ave. Duration:
7h 45m
Frequency:
3 times a day
Estimated price:
$13.04–$45.55
Tas-Choapa
Phone:
+56 22 822 7509
Website:
turbus.cl/
Bus from Terminal Sur de Santiago to Terminal
Ave. Duration:
7h 30m
Frequency:
Twice daily
Estimated price:
$35.42
Condor Bus
Phone:
+56 22 822 7528
Email:
clientescondor@condorbus.cl
Website:
condorbus.cl/
Bus from Terminal de Buses La Serena to La
Ave. Duration:
4h 55m
Frequency:
Once daily
Estimated price:
$10.87–$22.83
Bus from Terminal de Buses La Serena to Terminal
Ave. Duration:
6h 30m
Frequency:
4 times a day
Estimated price:
$14.13–$26.09
Andimar
Phone:
+56 22 683 8528
Email:
hola@andimar.cl
Website:
andimar.cl/
Bus from Terminal de Buses La Serena to Pichidangui
Ave. Duration:
3h 20m
Frequency:
Hourly
Estimated price:
$7.07–$17.39
Bus from Pichidangui - Cruce to Terminal
Ave. Duration:
2h 50m
Frequency:
Hourly
Estimated price:
$4.35–$11.96
Expreso Norte
Phone:
+56 2 3304 8632
Website:
expresonorte.cl/
Bus from Pichidangui - Cruce to Terminal
Ave. Duration:
2h 30m
Frequency:
3 times a day
Estimated price:
$8.10–$13.04
Buses Ahumada
Phone:
600 360 0224
Email:
contacto@busesahumada.cl
Website:
busesahumada.cl/busesahumada.cl/webv/
Bus from Los Andes to Terminal
Ave. Duration:
4h 30m
Frequency:
Once daily
Estimated price:
$4.46–$35.87
Nevada Internacional
Email:
nevadainternacionalmza@hotmail.com
Website:
mathostour.cl/2011/12/nevada-internacional.html
Bus from Terminal Sur de Santiago to Terminal
Ave. Duration:
6h
Frequency:
Twice daily
Estimated price:
$40.49
Sol del Pacifico
Phone:
+56 32 279 5700
Email:
secretaria@soldelpacifico.cl
Website:
soldelpacifico.cl/inicio
Bus from La Calera to Los
Ave. Duration:
1h 10m
Frequency:
Every 2 hours
Estimated price:
$2.17–$5.43
Questions and Answers
What is the cheapest way to get from La Serena to Mendoza?
The cheapest way to get from La Serena to Mendoza is to bus via Quilimarí which costs $25 - $81.52 and takes 15h 44m.
What is the fastest way to get from La Serena to Mendoza?
The fastest way to get from La Serena to Mendoza is to fly which takes 3h 16m and costs $141.30 - $336.96 .
Is there a direct bus between La Serena and Mendoza?
No, there is no direct bus from La Serena to Mendoza. However, there are services departing from Terminal de Buses La Serena and arriving at Terminal Mendoza via La Calera and Los Andes. The journey, including transfers, takes approximately 12h 19m.
How far is it from La Serena to Mendoza?
The distance between La Serena and Mendoza is 411 km. The road distance is 705.6 km.
How do I travel from La Serena to Mendoza without a car?
The best way to get from La Serena to Mendoza without a car is to bus via La Calera which takes 12h 19m and costs $17.39 - $76.09 .
How long does it take to get from La Serena to Mendoza?
It takes approximately 3h 16m to get from La Serena to Mendoza, including transfers.
Where do I catch the La Serena to Mendoza bus from?
La Serena to Mendoza bus services, operated by Pullman Bus, depart from Terminal de Buses La Serena station.
Train, bus or fly from La Serena to Mendoza?
The best way to get from La Serena to Mendoza is to fly which takes 3h 16m and costs $141.30 - $336.96 . Alternatively, you can bus via La Calera, which costs $17.39 - $76.09 and takes 12h 19m. There are no good options to train between La Serena to Mendoza.
Where does the La Serena to Mendoza bus arrive?
La Serena to Mendoza bus services, operated by Pullman Bus, arrive at La Calera station.
Can I drive from La Serena to Mendoza?
Yes, the driving distance between La Serena to Mendoza is 706 km. It takes approximately 7h 51m to drive from La Serena to Mendoza.
Where can I stay near Mendoza?
There are 3530+ hotels available in Mendoza. Prices start at $50.99 per night.
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